I agree, "make a plan and stick to it". It's very easy to break off from the game plan and take more risk then you initially intended. Creating and sticking to a plan is very important. Bad things happen to those that do not stick to some sort of plan. That sounds harsh. A 60% loss in minutes is not pleasing to anyone. Sometimes it can go as fast as it can come.
With those biotechs, I have found that the best way to play them is buy both longrange put and call options and be patient. If the news is good, the calls are exercised. If it is bad, the puts are. Or you can buy a small long stock position and a put and wait it out. Either way, it's best to close out most or all of the positon quickly once the news hits and the stock either swells up dramatically or sells off hard at the next market open. The news is almost always released outside of market hours, so you're likely out of luck on most (if not all) of the dramatic swing if you didn't already own the stock, the short position, or the options going into that day.
Although it may seem obvious, as you say a lot of people don't think of this, instead trying to sell whatever they believe will make the most profit, the fastest. However as you say, the thing which will make you the most profit, fast is that which you have a real interest in. A real passion for selling.
That is awesome advice, keeping it in my brain, injecting maybe, if i don't know too, i ask, research until i get it right, talking in light of real estate business, just learning how to knot the ropes